Symptoms may include:

• tingling or burning in the fingertips, toes and lips
• muscle aches or cramps
• twitching or spasms of the muscles
• fatigue or weakness
• painful menstruation
• patchy hair loss
• thinning of the eyebrows
• dry, course skin
• anxiety or nervousness
• headaches
• depression and other mood changes

Causes may include:

• hereditary hypoparathyroidism - either the parathyroid glands are not present at birth or they do not work properly. This inherited genetic disorder is passed to a child through a recessive gene.
• acquired hypoparathyroidism - tends to develop after accidental damage to or removal of the parathyroid glands during surgery. 

Other causes may include:

• extensive cancer radiation treatment of the face or neck
• Low levels of magnesium in the blood
• metabolic alkalosis – a condition in which there are chemical imbalances in the bloodstream

Treatment may include:

• medication
• Vitamin D
• Dietary changes
• hospitalization